Article
[Polymorphism of glutathion-S-transferase genes in patients with prostatic cancer].
Urologiia (Moscow, Russia : 1999) - 1 Jan 2000
Davydova N A, Dmitrieva A I, Selivanov S P, Tkachenko S B, Kovalik T A, Kolomiets S A, Sevast'ianova N V, Novitskiĭ V V
Abstract excerpt
The study of polymorphic variants of GSTT1, GSTM1 and GSTP1 genes from 61 patients with prostatic cancer (PC) has shown that incidence of 0/0 genotype GSTT1 and GSTM1 in PC patients was significantly higher of that in healthy men (n = 100) (34.4 and 15% in p = 0.007 and 60.7 and 43% in p = 0.04, respectively). PC risk in carriers of a GSTT1 deletion form was 2.97, CI95%--1.3-6.84, GSTM1--2.04 in CI95% 1.02-4.1....
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