Article
Hypermethylation of the HLA-G promoter is associated with preeclampsia.
Molecular human reproduction - 1 Sept 2015
Tang Yao, Liu Haiyan, Li Han, Peng Ting, Gu Weirong, Li Xiaotian
Abstract excerpt
Preeclampsia (PE) is a severe pregnancy-induced disorder characterized by hypertension and proteinuria and a leading cause of perinatal maternal-fetal mortality and morbidity in developing countries. Dysregulated human leukocyte antigen (HLA)-G was found in placentas as well as in maternal sera from PE patients; however, the reason for this difference is unknown. As accumulating evidence has confirmed that DNA...
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