Article
Genetic Changes to a Transcriptional Silencer Element Confers Phenotypic Diversity within and between Drosophila Species.
PLoS genetics - 1 Jun 2015
Johnson Winslow C, Ordway Alison J, Watada Masayoshi, Pruitt Jonathan N, Williams Thomas M, Rebeiz Mark
Abstract excerpt
The modification of transcriptional regulation has become increasingly appreciated as a major contributor to morphological evolution. However, the role of negative-acting control elements (e.g. silencers) in generating morphological diversity has been generally overlooked relative to positive-acting "enhancer" elements. The highly variable body coloration patterns among Drosophilid insects represents a powerful...
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