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Widespread cis- and trans-regulatory evolution underlies the origin, diversification, and loss of a sexually dimorphic fruit fly pigmentation trait.

Journal of experimental zoology. Part B, Molecular and developmental evolution - 1 Mar 2023

Hughes Jesse T, Williams Melissa E, Rebeiz Mark, Williams Thomas M

Abstract excerpt

Changes in gene expression are a prominent feature of morphological evolution. These changes occur to hierarchical gene regulatory networks (GRNs) of transcription factor genes that regulate the expression of trait-building differentiation genes. While changes in the expression of differentiation genes are essential to phenotypic evolution, they can be caused by mutations within cis-regulatory elements (CREs)...

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PMID: 34254440
DOI: 10.1002/jez.b.23068

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