Article
The Diagnostic and Prognostic Role of Interleukin 12B and Interleukin 6R Gene Polymorphism in Patients With Ankylosing Spondylitis.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases - 1 Jan 2018
Ruan Wen-Feng, Xie Jiang-Tao, Jin Qi, Wang Wen-Da, Ping An-Song
Abstract excerpt
OBJECTIVES: Interleukin 23 (IL-23) pathway and IL-1 cluster genes play prominent role in the etiopathology of ankylosing spondylitis (AS). The aim of this study was to investigate the diagnostic and prognostic role of 5 single-nucleotide polymorphisms related to IL-23 pathway and IL-1 cluster genes in AS patients. METHODS: Four hundred thirty-one patients with AS and 206 age- and sex-matched healthy controls were...
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