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Article

Prevalence and Clinicopathological Characteristics of HER2 and BRAF Mutation in Chinese Patients with Lung Adenocarcinoma.

PloS one - 1 Jan 2015

Shan Ling, Qiu Tian, Ling Yun, Guo Lei, Zheng Bo, Wang Bingning, Li Wenbin, Li Lin, Ying Jianming

Abstract excerpt

AIMS: To determine the prevalence and clinicopathological characteristics of BRAF V600E mutation and HER2 exon 20 insertions in Chinese lung adenocarcinoma (ADC) patients. METHODS: Given the fact that the driver mutations are mutually exclusive in lung ADCs, 204 EGFR/KRAS wild-type cases were enrolled in this study. Direct Sanger sequencing was performed to examine BRAF V600E and HER2 exon 20 mutations. The...

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Identifiers

PMID: 26102513
DOI: 10.1371/journal.pone.0130447
PMCID: PMC4477932

Genes

BRAF
EGFR
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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