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Article

Clinical, immunophenotypic, and molecular characteristics of well-differentiated systemic mastocytosis.

The Journal of allergy and clinical immunology - 1 Jan 2016

Álvarez-Twose Iván, Jara-Acevedo María, Morgado José Mário, García-Montero Andrés, Sánchez-Muñoz Laura, Teodósio Cristina, Matito Almudena, Mayado Andrea, Caldas Carolina, Mollejo Manuela, Orfao Alberto, Escribano Luis

Abstract excerpt

BACKGROUND: Well-differentiated systemic mastocytosis (WDSM) is a rare variant of systemic mastocytosis (SM) characterized by bone marrow (BM) infiltration by mature-appearing mast cells (MCs) often lacking exon 17 KIT mutations. Because of its rarity, the clinical and biological features of WDSM remain poorly defined. OBJECTIVE: We sought to determine the clinical, biological, and molecular features of a cohort...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26100086
DOI: 10.1016/j.jaci.2015.05.008

Genes

KIT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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