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Associations between peroxisome proliferator-activated receptor γ (PPAR-γ) polymorphisms and serum lipids: Two cross-sectional studies of community-dwelling adults.

Gene - 15 Dec 2020

Matsunaga Takashi, Naito Mariko, Yin Guang, Hishida Asahi, Okada Rieko, Kawai Sayo, Sasakabe Tae, Kadomatsu Yuka, Tsukamoto Mineko, Kubo Yoko, Tamura Takashi, Takeuchi Kenji, Mori Atsuyoshi, Hamajima Nobuyuki, Wakai Kenji

Abstract excerpt

Dyslipidemia is a well-established risk factor for cardiovascular disease. Experimental studies have reported that peroxisome proliferator-activated receptor γ (PPAR-γ) regulates adipocyte differentiation, lipid storage, and glucose metabolism. Therefore, we examined the associations between PPAR-γ polymorphisms (rs1801282, rs3856806, rs12497191, rs1151999, and rs1152003) and serum lipids in two cross-sectional...

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Topics

Adult
Aged
Cholesterol
Dyslipidemias
Female
Humans
Independent Living
Lipoproteins, LDL
Male
Middle Aged
PPAR gamma
Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 32755657
DOI: 10.1016/j.gene.2020.145019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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