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Article

Metabolic reprogramming supports the invasive phenotype in malignant melanoma.

Cancer letters - 28 Sept 2015

Bettum Ingrid J, Gorad Saurabh S, Barkovskaya Anna, Pettersen Solveig, Moestue Siver A, Vasiliauskaite Kotryna, Tenstad Ellen, Øyjord Tove, Risa Øystein, Nygaard Vigdis, Mælandsmo Gunhild M, Prasmickaite Lina

Abstract excerpt

Invasiveness is a hallmark of aggressive cancer like malignant melanoma, and factors involved in acquisition or maintenance of an invasive phenotype are attractive targets for therapy. We investigated melanoma phenotype modulation induced by the metastasis-promoting microenvironmental protein S100A4, focusing on the relationship between enhanced cellular motility, dedifferentiation and metabolic changes. In...

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Identifiers

PMID: 26095603
DOI: 10.1016/j.canlet.2015.06.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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