Article
Comparison of the Pathogenesis of the Angola and Ravn Strains of Marburg Virus in the Outbred Guinea Pig Model.
The Journal of infectious diseases - 1 Oct 2015
Cross Robert W, Fenton Karla A, Geisbert Joan B, Ebihara Hideki, Mire Chad E, Geisbert Thomas W
Abstract excerpt
BACKGROUND: Phylogenetic comparisons of known Marburg virus (MARV) strains reveal 2 distinct genetic lineages: Ravn and the Lake Victoria Marburg complex (eg, Musoke, Popp, and Angola strains). Nucleotide variances of >20% between Ravn and other MARV genomes suggest that differing virulence between lineages may accompany this genetic divergence. To date, there exists limited systematic experimental evidence of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
