Article
The African strain of Zika virus causes more severe in utero infection than Asian strain in a porcine fetal transmission model
1 Jan 2019
Abstract excerpt
Studies in mice showed that African Zika virus (ZIKV) strains cause more damage in embryos. These studies, however, were limited to the mouse-adapted African MR766 strain or infection at early gestation. Here, we compared infection of Asian and African strains in the fetal pig model at midgestation. Both strains caused fetal infection. ZIKV was detected in placenta, amniotic membrane, amniotic fluid, fetal blood,...
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