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DNA methylation provides insight into intergenerational risk for preterm birth in African Americans

19 Jun 2015

Abstract excerpt

African Americans are at increased risk for spontaneous preterm birth (PTB). Though PTB is heritable, genetic studies have not identified variants that account for its intergenerational risk, prompting the hypothesis that epigenetic factors may also contribute. The objective of this study was to evaluate DNA methylation from maternal leukocytes to identify patterns specific to PTB and its intergenerational risk....

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PMID: 26090903
DOI: 10.1080/15592294.2015.1062964

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