Article
A genome-wide association study identifies only two ancestry specific variants associated with spontaneous preterm birth.
Scientific reports - 9 Jan 2018
Rappoport Nadav, Toung Jonathan, Hadley Dexter, Wong Ronald J, Fujioka Kazumichi, Reuter Jason, Abbott Charles W, Oh Sam, Hu Donglei, Eng Celeste, Huntsman Scott, Bodian Dale L, Niederhuber John E, Hong Xiumei, Zhang Ge, Sikora-Wohfeld Weronika, Gignoux Christopher R, Wang Hui, Oehlert John, Jelliffe-Pawlowski Laura L, Gould Jeffrey B, Darmstadt Gary L, Wang Xiaobin, Bustamante Carlos D, Snyder Michael P, Ziv Elad, Patsopoulos Nikolaos A, Muglia Louis J, Burchard Esteban, Shaw Gary M, O'Brodovich Hugh M, Stevenson David K, Butte Atul J, Sirota Marina
Abstract excerpt
Preterm birth (PTB), or the delivery prior to 37 weeks of gestation, is a significant cause of infant morbidity and mortality. Although twin studies estimate that maternal genetic contributions account for approximately 30% of the incidence of PTB, and other studies reported fetal gene polymorphism association, to date no consistent associations have been identified. In this study, we performed the largest...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.