Article
RRM1, RRM2 and ERCC2 Gene Polymorphisms in Coronary Artery Disease.
In vivo (Athens, Greece) - 1 Jan 2000
Altinkilic Emre Murat, Isbir Selim, Gormus Uzay, Yilmaz Seda Gulec, Dalan Altay Burak, Duman Selvi, Isbir Turgay
Abstract excerpt
BACKGROUND/AIM: Coronary artery disease (CAD) is a chronic inflammatory disease seen as formation of atherosclerotic plaques (atheroma) in coronary arteries. Recent published papers show that DNA damage and repair mechanisms play a crucial role on the development and severity of atheromas. In this study, we investigated nucleotide excision repair (NER) pathway-related gene polymorphisms in atherosclerosis. XPD,...
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