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Article

ABCG2 gene polymorphisms as risk factors for atorvastatin adverse reactions: a case-control study.

Pharmacogenomics - 1 Jul 2015

Mirošević Skvrce Nikica, Macolić Šarinić Viola, Šimić Iveta, Ganoci Lana, Muačević Katanec Diana, Božina Nada

Abstract excerpt

AIM: To explore the association between dose-related adverse drug reactions (ADRs) of atorvastatin and polymorphisms of ABCG2, taking into account the influence of CYP3A4 and SLCO1B1 genes. MATERIALS & METHODS: Sixty patients who experienced atorvastatin dose-related ADRs and 90 matched patients without ADRs were enrolled in the study. Genotyping for ABCG2 421C > A, CYP3A4*22, SLCO1B1 388A > G, SLCO1B1 521T > C...

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Source

Identifiers

PMID: 26086347
DOI: 10.2217/pgs.15.47

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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