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Article

Novel mutations in the Myo5a gene cause a dilute coat color phenotype in mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Apr 2021

Zhang Hui, Wu Zhongping, Yang Lijuan, Zhang Zhen, Chen Hao, Ren Jun

Abstract excerpt

C57BL/6 laboratory mice usually show black coat color. We observed a dilute (gray) coat color phenotype in progenies of two C57BL/6 mice. This phenotype is inherited in an autosomal recessive mode. To uncover the molecular mechanism underlying this naturally occurring phenotypic variation, we performed whole-genome sequencing (25×) on 10 offspring of the two founder mice. The whole-genome DNA sequencing and...

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PMID: 33715225
DOI: 10.1096/fj.201903141RR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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