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TRIM8 downregulation in glioma affects cell proliferation and it is associated with patients survival

15 Jun 2015

Abstract excerpt

BACKGROUND: Human gliomas are a heterogeneous group of primary malignant brain tumors whose molecular pathogenesis is not yet solved. In this regard, a major research effort has been directed at identifying novel specific glioma-associated genes. Here, we investigated the effect of TRIM8 gene in glioma. METHODS: TRIM8 transcriptional level was profiled in our own glioma cases collection by qPCR and confirmed in...

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PMID: 26077989
DOI: 10.1186/s12885-015-1449-9

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