Article
TMEM158 promotes the proliferation and migration of glioma cells via STAT3 signaling in glioblastomas.
Cancer gene therapy - 1 Aug 2022
Li Jiabo, Wang Xuya, Chen Lulu, Zhang Jinhao, Zhang Yiming, Ren Xiao, Sun Jinzhang, Fan Xiaoguang, Fan Jikang, Li Tao, Tong Luqing, Yi Li, Chen Lei, Liu Jie, Shang Guanjie, Ren Xiude, Zhang Hao, Yu Shengping, Ming Haolang, Huang Qiang, Dong Jun, Zhang Chen, Yang Xuejun
Abstract excerpt
Glioblastoma is the most common primary intracranial malignant tumor in adults and has high morbidity and high mortality. TMEM158 has been reported to promote the progression of solid tumors. However, its potential role in glioma is still unclear. Here, we found that TMEM158 expression in human glioma cells in the tumor core was significantly higher than that in noncancerous cells at the tumor edge using...
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