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Article

TRIM8: Making the Right Decision between the Oncogene and Tumour Suppressor Role

28 Nov 2017

Abstract excerpt

The TRIM8/GERP protein is a member of the TRIM family defined by the presence of a common domain structure composed of a tripartite motif including a RING-finger, one or two B-box domains, and a coiled-coil motif. The TRIM8 gene maps on chromosome 10 within a region frequently found deleted and rearranged in tumours and transcribes a 3.0-kB mRNA. Its expression is mostly ubiquitously in murine and human tissues,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29182544
DOI: 10.3390/genes8120354

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