Article
New NCI-N87-derived human gastric epithelial line after human telomerase catalytic subunit over-expression.
World journal of gastroenterology - 7 Jun 2015
Saraiva-Pava Kathy, Navabi Nazanin, Skoog Emma C, Lindén Sara K, Oleastro Mónica, Roxo-Rosa Mónica
Abstract excerpt
AIM: To establish a cellular model correctly mimicking the gastric epithelium to overcome the limitation in the study of Helicobacter pylori (H. pylori) infection. METHODS: Aiming to overcome this limitation, clones of the heterogenic cancer-derived NCI-N87 cell line were isolated, by stably-transducing it with the human telomerase reverse-transcriptase (hTERT) catalytic subunit gene. The clones were first...
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