Article
Characterization of gastric adenocarcinoma cell lines established from CEA424/SV40 T antigen-transgenic mice with or without a human CEA transgene.
BMC cancer - 14 Mar 2006
Nöckel Jessica, van den Engel Natasja K, Winter Hauke, Hatz Rudolf A, Zimmermann Wolfgang, Kammerer Robert
Abstract excerpt
BACKGROUND: Gastric carcinoma is one of the most frequent cancers worldwide. Patients with gastric cancer at an advanced disease stage have a poor prognosis, due to the limited efficacy of available therapies. Therefore, the development of new therapies, like immunotherapy for the treatment of gastric cancer is of utmost importance. Since the usability of existing preclinical models for the evaluation of...
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