Article
Phenome-driven disease genetics prediction toward drug discovery.
Bioinformatics (Oxford, England) - 15 Jun 2015
Chen Yang, Li Li, Zhang Guo-Qiang, Xu Rong
Abstract excerpt
MOTIVATION: Discerning genetic contributions to diseases not only enhances our understanding of disease mechanisms, but also leads to translational opportunities for drug discovery. Recent computational approaches incorporate disease phenotypic similarities to improve the prediction power of disease gene discovery. However, most current studies used only one data source of human disease phenotype. We present an...
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