Article
Comparative analysis of a novel disease phenotype network based on clinical manifestations.
Journal of biomedical informatics - 1 Feb 2015
Chen Yang, Zhang Xiang, Zhang Guo-Qiang, Xu Rong
Abstract excerpt
Systems approaches to analyzing disease phenotype networks in combination with protein functional interaction networks have great potential in illuminating disease pathophysiological mechanisms. While many genetic networks are readily available, disease phenotype networks remain largely incomplete. In this study, we built a large-scale Disease Manifestation Network (DMN) from 50,543 highly accurate...
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