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Pathobiology of<i>Pneumocystis</i>pneumonia: life cycle, cell wall and cell signal transduction

12 Jun 2015

Abstract excerpt

Pneumocystis is a genus of ascomycetous fungi that are highly morbid pathogens in immunosuppressed humans and other mammals. Pneumocystis cannot easily be propagated in culture, which has greatly hindered understanding of its pathobiology. The Pneumocystis life cycle is intimately associated with its mammalian host lung environment, and life cycle progression is dependent on complex interactions with host...

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PMID: 26071598
DOI: 10.1093/femsyr/fov046

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