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<i>Pneumocystis jirovecii</i>infection: Cell wall (1→3)-β-D-glucan biology and diagnostic utility

21 Sept 2010

Abstract excerpt

Pneumocystis jirovecii has emerged as an important pulmonary pathogen. Historically associated with the immunocompromised, it is being increasingly observed in immunocompetent populations. (1→3)-ß-D-glucan (BG) is a major component of the cyst cell wall and plays an important role in the inflammatory response to the organism. Inflammatory synergy by co-stimulation with BG and Toll-like receptor ligands has been...

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PMID: 20854193
DOI: 10.3109/1040841x.2010.484001

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