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Multiparameter Analysis of Human Bone Marrow Stromal Cells Identifies Distinct Immunomodulatory and Differentiation-Competent Subtypes.

Stem cell reports - 9 Jun 2015

James Sally, Fox James, Afsari Farinaz, Lee Jennifer, Clough Sally, Knight Charlotte, Ashmore James, Ashton Peter, Preham Olivier, Hoogduijn Martin, Ponzoni Raquel De Almeida Rocha, Hancock Y, Coles Mark, Genever Paul

Abstract excerpt

Bone marrow stromal cells (BMSCs, also called bone-marrow-derived mesenchymal stromal cells) provide hematopoietic support and immunoregulation and contain a stem cell fraction capable of skeletogenic differentiation. We used immortalized human BMSC clonal lines for multi-level analysis of functional markers for BMSC subsets. All clones expressed typical BMSC cell-surface antigens; however, clones with trilineage...

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Identifiers

PMID: 26070611
DOI: 10.1016/j.stemcr.2015.05.005
PMCID: PMC4471830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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