Article
To bet or not to bet: deciphering cell to cell variation in protozoan infections.
Trends in parasitology - 1 Aug 2015
Seco-Hidalgo Víctor, Osuna Antonio, Pablos Luis Miguel De
Abstract excerpt
Some of the most crucial phenotypic aspects of parasites, such as an antigen-coated surface, parasite sexual differentiation, virulence, and drug resistance, rely on adaptive plasticity and/or stochastic events. At a population level, cell to cell variability represents an avenue for rapid response to drastic changes in the environment. Single cell approaches can be used to unravel the different strategies used...
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