Article
Detection of the KIT D816V mutation in peripheral blood of systemic mastocytosis: diagnostic implications.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2015
Jara-Acevedo Maria, Teodosio Cristina, Sanchez-Muñoz Laura, Álvarez-Twose Ivan, Mayado Andrea, Caldas Carolina, Matito Almudena, Morgado José M, Muñoz-González Javier I, Escribano Luis, Garcia-Montero Andrés C, Orfao Alberto
Abstract excerpt
Recent studies have found the KIT D816V mutation in peripheral blood of virtually all adult systemic mastocytosis patients once highly sensitive PCR techniques were used; thus, detection of the KIT D816V mutation in peripheral blood has been proposed to be included in the diagnostic work-up of systemic mastocytosis algorithms. However, the precise frequency of the mutation, the biological significance of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.