Article
Histological variety of gastric carcinoma and Helicobacter pylori cagA and vacA polymorphism.
European journal of gastroenterology & hepatology - 1 Sept 2015
Figura Natale, Valassina Marcello, Moretti Elena, Vindigni Carla, Collodel Giulia, Iacoponi Francesca, Giordano Nicola, Roviello Francesco, Marrelli Daniele
Abstract excerpt
BACKGROUND: Helicobacter pylori infection may increase the risk of both histotypes of gastric carcinoma (GC): intestinal (IGC) and diffuse (DGC). Polymorphism of the main H. pylori virulence factors, cagA and vacA, could have a different impact on the histological variety of GC. METHODS: Two hundred and twenty-six H. pylori colonies were examined from 28 GC patients: 15 with IGC and 13 with DGC. DNA was extracted...
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