Article
The bone marrow metastasis niche in retinoblastoma.
Cellular oncology (Dordrecht, Netherlands) - 1 Aug 2015
Khosravi Abbas, Shahrabi Saeid, Shahjahani Mohammad, Saki Najmaldin
Abstract excerpt
BACKGROUND: Retinoblastoma (Rb) is a progressive cancer which mainly occurs in children, and which is caused by different genetic or epigenetic alterations that lead to inactivation of both alleles of the RB1 gene. Hereditary and non-hereditary forms of Rb do exist, and the hereditary form is associated with an increased risk of secondary malignancies. Metastasis to distant organs is a critical feature of many...
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