Article

Novel germline RB1 and MET gene mutations in a case with bilateral retinoblastoma followed by multiple metastatic osteosarcoma

2020-11-11

Abstract excerpt

<h4>Background: </h4> Retinoblastoma (Rb) is a malignant tumor of the developing retina that affects children before the age of five years in association with inherited or early germline mutations of the RB1 gene. The genetic predisposition is also related with second primary malignancies arising de novo, or following radiotherapy which have become the leading cause of death in retinoblastoma survivors. Procedure...

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Identifiers and source

Literature Corpus work: 33a080cc-a44a-547d-998f-74bed0021db9
DOI: 10.22541/au.160507445.50849878/v1

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