Article
Molecular changes in endometriosis-associated ovarian clear cell carcinoma.
European journal of cancer (Oxford, England : 1990) - 1 Sept 2015
Worley Michael J, Liu Shubai, Hua Yuanyuan, Kwok Jamie Sui-Lam, Samuel Anicka, Hou Lei, Shoni Melina, Lu Shi, Sandberg Evelien M, Keryan Anna, Wu Di, Ng Shu-Kay, Kuo Winston P, Parra-Herran Carlos E, Tsui Stephen K W, Welch William, Crum Christopher, Berkowitz Ross S, Ng Shu-Wing
Abstract excerpt
BACKGROUND: Endometriosis is frequently associated with and thought of having propensity to develop into ovarian clear cell carcinoma (OCCC), although the molecular transformation mechanism is not completely understood. METHODS: We employed immunohistochemical (IHC) staining for marker expression along the potential progression continuum. Expression profiling of microdissected endometriotic and OCCC cells from...
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