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Article

Developing an animal model of Dupuytren's disease by orthotopic transplantation of human fibroblasts into athymic rat.

BMC musculoskeletal disorders - 7 Jun 2015

Satish Latha, Palmer Bradley, Liu Fang, Papatheodorou Loukia, Rigatti Lora, Baratz Mark E, Kathju Sandeep

Abstract excerpt

BACKGROUND: Dupuytren's disease (DD) is a slow, progressive fibroproliferative disorder affecting the palms of the hands. The disease is characterized by the formation of collagen rich- cords which gradually shorten by the action of myofibroblasts resulting in finger contractures. It is a disease that is confined to humans, and a major limiting factor in investigating this disorder has been the lack of a faithful...

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Identifiers

PMID: 26049932
DOI: 10.1186/s12891-015-0597-z
PMCID: PMC4458343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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