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Article

Dupuytren's: a systems biology disease

1 Jan 2011

Abstract excerpt

Dupuytren's disease (DD) is an ill-defined fibroproliferative disorder of the palm of the hands leading to digital contracture. DD commonly occurs in individuals of northern European extraction. Cellular components and processes associated with DD pathogenesis include altered gene and protein expression of cytokines, growth factors, adhesion molecules, and extracellular matrix components. Histology has shown...

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PMID: 21943049
DOI: 10.1186/ar3438

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