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Article

Deletion of the DNA Ligase IV Gene in Candida glabrata Significantly Increases Gene-Targeting Efficiency.

Eukaryotic cell - 1 Aug 2015

Cen Yuke, Fiori Alessandro, Van Dijck Patrick

Abstract excerpt

Candida glabrata is reported as the second most prevalent human opportunistic fungal pathogen in the United States. Over the last decades, its incidence increased, whereas that of Candida albicans decreased slightly. One of the main reasons for this shift is attributed to the inherent tolerance of C. glabrata toward the commonly used azole antifungal drugs. Despite a close phylogenetic distance to Saccharomyces...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26048009
DOI: 10.1128/EC.00281-14
PMCID: PMC4519754

Genes

LIG4

Provenance

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