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Article

GDNF and NT-3 induce progenitor bone mesenchymal stem cell differentiation into neurons in fetal gut culture medium.

Cellular and molecular neurobiology - 1 Mar 2015

Zhu Tianqi, Yu Donghai, Feng Jiexiong, Wu Xiaojuan, Xiang Lei, Gao Heyun, Zhang Xueqin, Wei Mingfa

Abstract excerpt

With the increasing use of bone marrow mesenchymal stem cells (BMSCs) in cell therapies, factors regulating BMSC differentiation have become the interest of current research. In this study, we investigated the effects of glial cell-derived neurotrophic factor (GDNF) and neurotrophin-3 (NT-3) on the course of BMSC differentiation. BMSCs were isolated from rat bone marrow and transfected with GDNF and NT-3 genes....

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Source

Identifiers

PMID: 25301495
DOI: 10.1007/s10571-014-0120-3

Genes

GDNF
GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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