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Article

Genetics in non-alcoholic fatty liver disease: The role of risk alleles through the lens of immune response.

Clinical and molecular hepatology - 1 Feb 2023

Sookoian Silvia, Pirola Carlos J

Abstract excerpt

The knowledge on the genetic component of non-alcoholic fatty liver disease (NAFLD) has grown exponentially over the last 10 to 15 years. This review summarizes the current evidence and the latest developments in the genetics of NAFLD and non-alcoholic steatohepatitis (NASH) from the immune system's perspective. Activation of innate and or adaptive immune response is an essential driver of NAFLD disease severity...

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Identifiers

PMID: 36472053
DOI: 10.3350/cmh.2022.0318
PMCID: PMC10029961

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