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Article

Linkage Analysis in Autoimmune Addison's Disease: NFATC1 as a Potential Novel Susceptibility Locus.

PloS one - 1 Jan 2015

Mitchell Anna L, Bøe Wolff Anette, MacArthur Katie, Weaver Jolanta U, Vaidya Bijay, Erichsen Martina M, Darlay Rebecca, Husebye Eystein S, Cordell Heather J, Pearce Simon H S

Abstract excerpt

BACKGROUND: Autoimmune Addison's disease (AAD) is a rare, highly heritable autoimmune endocrinopathy. It is possible that there may be some highly penetrant variants which confer disease susceptibility that have yet to be discovered. METHODS: DNA samples from 23 multiplex AAD pedigrees from the UK and Norway (50 cases, 67 controls) were genotyped on the Affymetrix SNP 6.0 array. Linkage analysis was performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26042420
DOI: 10.1371/journal.pone.0123550
PMCID: PMC4456164

Genes

NFATC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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