Article
Association of mtDNA M/N haplogroups with systemic lupus erythematosus: a case-control study of Han Chinese women.
Scientific reports - 3 Jun 2015
Tang Youzhou, Wang Li, Zhu Min, Yang Ming, Zhong Kuangbiao, Du Qing, Zhang Hao, Gui Ming
Abstract excerpt
To investigate whether mitochondrial DNA haplogroups M or N are related to occurrence or manifestations of systemic lupus erythematosus (SLE), we collected M/N haplogrouping and clinical characteristics from 868 Han Chinese women with SLE, as well as for 870 age-matched healthy Han Chinese control women. M/N haplogroups were determined in all subjects using allele-specific amplification. The frequency of M...
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