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Article

A genetic screen reveals a periplasmic copper chaperone required for nitrite reductase activity in pathogenic Neisseria.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Sept 2015

Jen Freda E-C, Djoko Karrera Y, Bent Stephen J, Day Christopher J, McEwan Alastair G, Jennings Michael P

Abstract excerpt

Under conditions of low oxygen availability, Neisseria meningitidis and Neisseria gonorrhoeae are able to respire via a partial denitrification pathway in which nitrite is converted to nitrous oxide. In this process, nitrite reductase (AniA), a copper (Cu)-containing protein converts nitrite to NO, and this product is converted to nitrous oxide by nitric oxide reductase (NorB). NorB also confers protection...

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Identifiers

PMID: 26031293
DOI: 10.1096/fj.15-270751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A genetic screen reveals a periplasmic copper chaperone required for nitrite reductase activity in pathogenic Neisseria.PMID 26031293Read ↗

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