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Article

High level PHGDH expression in breast is predominantly associated with keratin 5‐positive cell lineage independently of malignancy

14 May 2015

Abstract excerpt

We have previously reported the 2D PAGE-based proteomic profiling of a prospective cohort of 78 triple negative breast cancer (TNBC) patients, and the establishment of a cumulative TNBC protein database. Analysis of this database identified a number of proteins as being specifically overexpressed in TNBC samples. One such protein was D-3-phosphoglycerate dehydrogenase (Phgdh), a candidate oncogene. We analysed...

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PMID: 26026368
DOI: 10.1016/j.molonc.2015.05.003

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