Article
QVZ: lossy compression of quality values.
Bioinformatics (Oxford, England) - 1 Oct 2015
Malysa Greg, Hernaez Mikel, Ochoa Idoia, Rao Milind, Ganesan Karthik, Weissman Tsachy
Abstract excerpt
MOTIVATION: Recent advancements in sequencing technology have led to a drastic reduction in the cost of sequencing a genome. This has generated an unprecedented amount of genomic data that must be stored, processed and transmitted. To facilitate this effort, we propose a new lossy compressor for the quality values presented in genomic data files (e.g. FASTQ and SAM files), which comprise roughly half of the...
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