Article
QualComp: a new lossy compressor for quality scores based on rate distortion theory.
BMC bioinformatics - 8 Jun 2013
Ochoa Idoia, Asnani Himanshu, Bharadia Dinesh, Chowdhury Mainak, Weissman Tsachy, Yona Golan
Abstract excerpt
BACKGROUND: Next Generation Sequencing technologies have revolutionized many fields in biology by reducing the time and cost required for sequencing. As a result, large amounts of sequencing data are being generated. A typical sequencing data file may occupy tens or even hundreds of gigabytes of disk space, prohibitively large for many users. This data consists of both the nucleotide sequences and per-base...
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