A variant of PSMD6 is associated with the therapeutic efficacy of oral antidiabetic drugs in Chinese type 2 diabetes patients.

doi:10.1038/srep10701

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Article

A variant of PSMD6 is associated with the therapeutic efficacy of oral antidiabetic drugs in Chinese type 2 diabetes patients.

Scientific reports - 29 May 2015

Chen Miao, Hu Cheng, Zhang Rong, Jiang Feng, Wang Jie, Peng Danfeng, Tang Shanshan, Sun Xue, Yan Jing, Wang Shiyun, Wang Tao, Bao Yuqian, Jia Weiping

Abstract excerpt

The PSMD6 variant rs831571 has been identified as a susceptibility locus for type 2 diabetes mellitus (T2DM). This study aimed to investigate the association of this variant with therapeutic effects of oral antidiabetic drugs in Chinese T2DM patients. 209 newly diagnosed T2DM patients were randomly assigned to treatment with repaglinide or rosiglitazone for 48 weeks, and the therapeutic effects were compared. In...

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Identifiers

PMID: 26024304
DOI: 10.1038/srep10701
PMCID: PMC4448652

Genes

PSMD6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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