Article
Direct Detection by the Xpert MTB/RIF Assay and Characterization of Multi and Poly Drug-Resistant Tuberculosis in Guinea-Bissau, West Africa.
PloS one - 1 Jan 2015
Rabna Paulo, Ramos Jorge, Ponce Gema, Sanca Lilica, Mané Morto, Armada Ana, Machado Diana, Vieira Fina, Gomes Victor F, Martins Elisabete, Colombatti Raffaella, Riccardi Fabio, Perdigão João, Sotero Joana, Portugal Isabel, Couto Isabel, Atouguia Jorge, Rodrigues Amabélia, Viveiros Miguel
Abstract excerpt
BACKGROUND: This study aimed to evaluate the usefulness of the Xpert MTB/RIF assay for the rapid direct detection of M. tuberculosis complex (MTBC) strains and rifampicin resistance associated mutations in a resource-limited setting such as Guinea-Bissau and its implications in the management of tuberculosis (TB) and drug resistant tuberculosis, complementing the scarce information on resistance and genotypic...
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