Phase-Variable Control of Multiple Phenotypes in Acinetobacter baumannii Strain AB5075.

doi:10.1128/JB.00188-15

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Article

Phase-Variable Control of Multiple Phenotypes in Acinetobacter baumannii Strain AB5075.

Journal of bacteriology - 1 Aug 2015

Tipton Kyle A, Dimitrova Daniela, Rather Philip N

Abstract excerpt

UNLABELLED: Acinetobacter baumannii strain AB5075 produces colonies with two opacity phenotypes, designated opaque and translucent. These phenotypes were unstable and opaque and translucent colony variants were observed to interconvert at high frequency, suggesting that a phase-variable mechanism was responsible. The frequency of phase variation both within colonies and in broth cultures increased in a cell...

Topics

Acinetobacter baumannii
Anti-Bacterial Agents
Biofilms
Drug Resistance, Bacterial
Gene Expression Regulation, Bacterial
Phenotype
Virulence

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Identifiers

PMID: 26013481
DOI: 10.1128/JB.00188-15
PMCID: PMC4518826

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