Article
A LysR-Type Transcriptional Regulator Controls Multiple Phenotypes in Acinetobacter baumannii.
Frontiers in cellular and infection microbiology - 1 Jan 2021
Tierney Aimee R P, Chin Chui Yoke, Weiss David S, Rather Philip N
Abstract excerpt
Acinetobacter baumannii is a multidrug-resistant, Gram-negative nosocomial pathogen that exhibits phenotypic heterogeneity resulting in virulent opaque (VIR-O) and avirulent translucent (AV-T) colony variants. Each variant has a distinct gene expression profile resulting in multiple phenotypic differences. Cells interconvert between the VIR-O and AV-T variants at high frequency under laboratory conditions,...
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