Article
The exposome in inflammatory bowel disease.
Tropical gastroenterology : official journal of the Digestive Diseases Foundation - 1 Jan 2000
Ananthakrishnan Ashwin N
Abstract excerpt
Inflammatory bowel disease (IBD) including Crohn's disease (CD) and ulcerative colitis (UC), is an immunologically mediated chronic disease. The key underlying pathology is a deregulated immune response to commensal flora in a genetically susceptible host. Advances in genomics, epigenomics and understanding of the microbiome have brought forth the role of these spheres in the pathogenesis of IBD. Yet these...
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