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Article

Impact of the Exposome on the Epigenome in Inflammatory Bowel Disease Patients and Animal Models

9 Jul 2022

Abstract excerpt

Inflammatory bowel diseases (IBD) are chronic inflammatory disorders of the gastrointestinal tract that encompass two main phenotypes, namely Crohn's disease and ulcerative colitis. These conditions occur in genetically predisposed individuals in response to environmental factors. Epigenetics, acting by DNA methylation, post-translational histones modifications or by non-coding RNAs, could explain how the...

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PMID: 35886959
DOI: 10.3390/ijms23147611

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