Article
TP53 transcription factor for the NEDD9/HEF1/Cas-L gene: potential targets in Non-Small Cell Lung Cancer treatment.
Scientific reports - 26 May 2015
Rousseau Bénédicte, Jacquot Catherine, Le Palabe Julie, Malleter Marine, Tomasoni Christophe, Boutard Tifenn, Sakanyan Vehary, Roussakis Christos
Abstract excerpt
Lung cancer is a serious public health problem. Although there has been significant progress in chemotherapy, non-small cell lung cancer is still resistant to current treatments, primarily because of the slow rate of cell development. It is thus important to find new molecules directed against targets other than proliferation agents. Considering the high proportion of mutant proteins in tumor cells, and the high...
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